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Osteoporosis Prevented By Hormone Replacement Therapy

Review on November 12, 2009

Osteoporosis HRT

Many women seek solace from postmenopausal symptoms by taking estrogen replacement therapy. Among the many benefits provided by hormone replacement therapy, aside from relief from hot flashes, loss of libido, vaginal dryness and night sweats, is the prevention of osteoporosis. This three year long survey of 135 postmenopausal women has served to show that the positive effects of estrogen replacement therapy do not stop at osteoporosis, they also have a positive effect of tooth loss.

Because of dropping levels of estrogen, many women are at an increased risk for developing osteoporosis after menopause. To combat osteoporosis and a slew of other unwanted side effects that come with menopause, many women turn to estrogen replacement therapy. Estrogen replacement therapy has many beneficial effects on postmenopausal users including improving postcranial bone density that further aids in the prevention of osteoporosis.

It is presumed that one result of estrogen deficiency is oral bone loss. A examination was performed that revealed that tooth loss was more prevalent in females with osteoporosis and lower bone mineral density than those without. Survey members with osteoporosis were also more likely to use dentures and experience tooth loss than those without. Thus the assumption that bone loss leads to tooth loss in postmenopausal women, with an added consequence of oral bone loss was created.

Osteoporosis tooth

Osteoporosis is often caused by estrogen deficiency. Scientific findings also imply that estrogen deficiency may increase the possibility of tooth loss in comparison to estrogen sufficiency. After reviewing the results of three large observational studies, the potential beneficial effect of hormone replacement therapy on the dental health of postmenopausal women was verified. Hormone replacement therapy users had a higher number of teeth and lower cases of denture use or tooth loss than non hormone replacement therapy patients.

One hundred and thirty five postmenopausal women between the ages of 41 to 70 participated in this analysis. Each participant had no evidence of periodontal disease prior to the study. They were randomly prescribed hormone replacement therapy of the placebo drug.

Data was used from the Postmenopausal Estrogen/Progestin Interventions Trial. After 12 months of treatment there was a noticeable increase of alveolar bone mass and alveolar crest height in hormone replacement therapy users. Overall results from this study show the dental attachment apparatus is made stronger by hormone replacement therapy in postmenopausal women.


Sources:
  • PharmD, PhD, Lee, Euni; PharmD Zuckerman, Ilene H.; PhD Weiss, Sheila R. "Patterns of Pharmacotherapy and Counseling for Osteoporosis Management in Visits to US Ambulatory Care Physicians by Women." (2002). Arch Intern Med.